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Zhewitra 40 mg, like other PDE5 inhibitors, may interact with certain medications, including nitrates, alpha-blockers, and some antifungal and antibiotic drugs. These interactions can potentially lead to serious adverse effects such as sudden drops in blood pressure, which may be life-threatening. It's essential to inform your healthcare provider about all medications you are currently taking, including over-the-counter Zhewitra 40 mg drugs and supplements, to avoid harmful interactions. Additionally, individuals with certain medical conditions, such as severe liver or kidney disease, uncontrolled hypertension, or a recent history of stroke or heart attack, may not be suitable candidates for treatment with Zhewitra 40 mg.

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